We’ve got just the thing. Our probiotic spores can survive almost any production process your throw at them, in supplements too.
Class: Probiotic
Format: Powder
ProSilience™ HU58™

Novonesis' ProSilience™ HU58™ is a spore probiotic that offers clinically demonstrated benefits for immune system and digestive health. The probiotic is of the species Bacillus subtilis which has superior stability in food and beverage processing, as well as in the final product during shelf-life.
Product features, details and benefits
- Supports gut and immune health
- Delivers 1 billion CFU through end of product shelf-life thanks to high resilience in its spore format
- Survives pasteurization, boiling water and other heat-applications, enabling stable use in RTDs
- Offers superior stability to other spore probiotics on the market
ProSilience™ HU58™ is a strain of Bacillus subtilis which has more than ten years' history of safe use in supplements and has clinically demonstrated health benefits supporting immune and digestive health.
ProSilience™ HU58™ is available in 1 kg and 5 kg packages of 15Bn CFU/g. It’s convenient for dosing in food and beverage applications.
This product contains microbials. While microbial products are safe to use in consumer applications, they must be handled correctly in production environments to ensure that workers do not inhale organic dust and bioaerosols.
Please follow the precautionary handling recommendations below:
- Avoid breathing dust/fume/gas/mist/vapors/spray
- Avoid contact with eyes, skin, or clothing
- In case of inadequate ventilation wear respiratory protection
- IF INHALED: Remove person to fresh air and keep comfortable for breathing
- Store in a dry place. Store in a closed container
- Dispose of contents/containers in accordance with local regulations
For recommendations on how to safely handle the microbial product, please visit the guide.
Explore the clinical evidence behind ProSilience™ HU58™
For centuries, Bacillus subtilis strains have played a key role in traditional Asian and West African fermented foods, improving digestibility and boosting nutritional value1.
ProSilience™ HU58™ marks the next step in probiotic solutions. Backed by pre-clinical and clinical studies, ProSilience™ HU58™ helps you transform your products with claims that build consumer trust and drive innovation in the beverage industry.
This isn’t just science – it’s the future of functional beverages. Download our clinical summary to learn more about ProSilience™ HU58™ and join a healthier tomorrow.

A robust probiotic spore for your preferred format
Earning consumer loyalty is essential for food and beverage producers, and ProSilience™ HU58™ is here to make it happen.
This highly stable, food-grade probiotic ensures that your products deliver gut-health benefits right up to the end of their shelf life.
The result? Affordable solutions that build trust and keep your customers coming back.

Looking for probiotic spores for supplements?
Looking for probiotic spores for supplements?
Consumers are thirsty for probiotics
On a fall Tuesday, we hosted an explorative night on probiotics and gut wellness for health enthusiasts.
Watch the video to learn how these consumers perceive probiotics and how they prioritize gut health.
Testing one of our products in your own production is the best way to experience all the benefits. Request a sample now.
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