Mental health

Mental health is top of mind

We’re all interested in having a better and happier life. And consumers are looking to the emerging science of probiotics and the gut-brain axis for answers¹.

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Mental wellness

There is no health without mental health

80% of consumers globally want to do more to look after their mental well-being². But what does that mean?

The World Health Organization (WHO) describes mental health as a “state of well-being in which the individual realizes their own abilities, can cope with the normal stresses of life, can work productively and is able to make a contribution to their community”³.

No wonder people are looking for ways to actively support the mind’s ability to thrive. The days of taboo and stigma are behind us, and you can seize this opportunity with innovative and effective biotic solutions.

The mental health supplement market is booming

9 billion$

Size of mental health retail market size⁴

Compound annual growth rate⁴

See our solution for mental wellness

Can’t wait to read about ProbioBrain™, with our unique Bifidobacterium longum 1714™, psychobiotic strain?

Mental wellness ProbioBrain™ product page

A “Psychobiotic” is a bacterium, when ingested in adequate amount, has a positive benefit for mental health.

Ted Dinan, M.D., Ph.D, John F. Cryan, Ph.D
APC Microbiome Ireland, University College Cork

What’s on your mind?

Whatever it is, let us know. Together, we can put people on a track towards robust immunity. It’s a question of better health.

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How the microbiome-gut-brain axis works

As old as a "gut feeling"

We’ve always known the gut and brain are connected, but science only recently began discovering how the rich and dynamic communication of microbial-gut-brain-axis works. In fact, most of the scientific breakthroughs were as recent as the 2010s and 2020s.

The quick overview

The brain and gut communicate in both directions. The brain affects gut function and the microbiome. And gut microbes produce molecules that influence brain function. This two-way link impacts our immunity, digestion, mood, cognitive capabilities, how we respond to stress, and even how we behave⁵ ⁶ ⁷.

Via the vagus nerve I

The vagus nerve is a long wandering nerve that runs from the brain stem to our organs, including the intestines.

The brain sends signals via it to the stomach. When we eat, for example, signals travel down the vagus nerve prompting the release of digestive juices and enzymes that help break down food⁸.

Via the vagus nerve II

The gut microbiome also uses the vagus nerve to communicate to the brain.

Certain gut microbes produce substances, for example, short-chain fatty acids (SCFA) and neurotransmitter precursors like serotonin that influence the vagus nerve to signal the brain and affect appetite, mood, and more⁹ ¹⁰.

Via the blood brain barrier

The blood brain barrier is a membrane that protects the brain by regulating what molecules can enter the brain.

Some metabolites produced by bacteria, in the intestine, like SCFA, can slip into the blood stream and cross the blood brain barrier to influence brain function¹¹ ¹².

Via hormone production

Stress affects the gut via the hypothalamic pituitary adrenal axis. It triggers a cascade of hormone production, for example cortisol. Cortisol can influence intestinal permeability, while other stress hormones affect the environment within the gut and the composition of the microbes that live there.¹³

Learn more about mental wellness here

Mental health brochure
Read more about this rapidly growing market and the scientific evidence behind ProbioBrain^TM, including its proposed mode of action.
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Disclaimer

This content is intended exclusively for business-to-business purposes for a professional audience only and is not intended to target consumers.