Class: Probiotic spore

Format: Multiple formats

B. subtilis HU58™ 

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B. subtilis, HU58™ (shortened to HU58™) belongs to the genus Bacillus, and is supported by a significant number of preclinical, clinical and safety studies. It has been shown in trials to have a positive influence on gastrointestinal health. 

HU58™ is a spore-forming probiotic strain, meaning it can enter a dormant state. In this dormant state, it is extremely robust and can withstand harsh manufacturing processes, including those used to make gummy supplements.

Product features, details and benefits

  • Clinically studied on children and adults.

  • May have positive affects on gut discomfort and occasional loose stools.

  • Suitable for gummy supplements.

The HU58™ strain was isolated from a healthy human microbiome at Royal Holloway University as part of Professor Simon Cutting’s research on bacterial spores. As a lactic-acid-producing bacterial strain, it was selected for its superior sporulation efficiency, strong adaptability to the gastrointestinal tract, and long-lasting activity. 

Spore-forming bacteria can survive very harsh conditions and processing like HTST pasteurization. 

It’s produced in a certified GMP Facility, FSSC22000 certified incl. ISO22000.

The HU58™ logo can be used on packaging subject to agreement. HU58™ is a trademark of Novozymes A/S, part of Novonesis Group.

This product contains microbials. While microbial products are safe to use in consumer applications, they must be handled correctly in production environments to ensure that workers do not inhale organic dust and bioaerosols.

Please follow the precautionary handling recommendations below:
• Avoid breathing dust/fume/gas/mist/vapors/spray
• Avoid contact with eyes, skin, or clothing
• In case of inadequate ventilation wear respiratory protection
• IF INHALED: Remove person to fresh air and keep comfortable for breathing
• Store in a dry place. Store in a closed container
• Dispose of contents/containers in accordance with local regulations

More information about safe-handling of microbial products is available on request.

For recommendations on how to safely handle the microbial product, please visit the guide.

Health benefits

HU58™ has been studied both alone (children) and in combination with SC208™ (adults), demonstrating the following health benefits: 

 

CHILDREN 

In children with occasional loose stools, HU58™ has been demonstrated to: 

  • Support faster resolution of the loose stools1
  • Reduce abdominal discomfort1
  • Improve general gut wellbeing1

 

ADULTS 

The combination of the HU58™ + SC208™ (link to SC208™ page) strains has been shown to: 

  • Promote gastrointestinal comfort2
  • Promotes normal stool consistency2 ,3 ,4
  • Supports gut health2
  • Shortens the duration of occasional loose stools234

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Opportunities with spores

Disclaimer

This content is intended exclusively for business-to-business purposes for a professional audience only and is not intended to target consumers.